Mozzarella Pesto Chicken Grilled Cheese

Featured in: Classic Comfort Dishes

This mouthwatering grilled cheese combines shredded chicken breast with vibrant basil pesto and layers of fresh mozzarella, all pressed to golden perfection on sourdough bread. Ready in just 20 minutes, it delivers a satisfying blend of American comfort and Italian flavors. Butter the bread, layer your ingredients, and cook until the cheese melts and the exterior turns crispy and golden. Perfect for lunch or a quick dinner.

Updated on Wed, 21 Jan 2026 12:22:00 GMT
Golden toasted sourdough grilled cheese with shredded chicken, vibrant pesto, and melted mozzarella on a rustic plate.  Pin it
Golden toasted sourdough grilled cheese with shredded chicken, vibrant pesto, and melted mozzarella on a rustic plate. | cozybatbout.com

The smell of butter hitting a hot skillet still stops me in my tracks every single time. I stumbled onto this combo during a rainy Tuesday when leftovers from Sunday's roast chicken met a jar of pesto I'd been meaning to use. Something about the way mozzarella melts into those vibrant basil oils just makes sense. My husband walked in from work and immediately asked if he could have whatever was creating that aroma.

Last summer, my sister was recovering from surgery and needed meals she could reheat easily. I made a batch of these, cut them into quarters, and stacked them in her fridge. She texted me two days later saying she'd eaten nothing else since I dropped them off. Sometimes the simplest combinations hit the hardest.

Ingredients

  • Sourdough or Italian bread: Sturdy enough to hold everything together without getting soggy, and it develops this incredible crunch when buttered and griddled
  • Fresh mozzarella: shredding it yourself melts better than pre-shredded, and the creaminess balances the pesto's brightness
  • Cooked shredded chicken breast: rotisserie chicken works perfectly here, or use leftover roast chicken for the most tender results
  • Basil pesto: homemade is lovely but a good quality store-bought version absolutely delivers the same punchy flavor
  • Unsalted butter softened: salted butter works too, just skip the Parmesan if you're watching sodium levels
  • Optional extras: tomato adds moisture, fresh basil brings an extra herbal pop, and Parmesan creates this savory umami crust

Instructions

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Spread the pesto foundation:
Lay out all four bread slices and generously spread about a tablespoon and a half of pesto onto two of them, going all the way to the edges so every bite gets that basil punch
Layer the chicken:
Distribute your shredded chicken evenly over the pesto-coated slices, pressing it gently into the sauce so it doesn't slide around during cooking
Add the cheese:
Layer your mozzarella over the chicken, and if you're using tomato and fresh basil, tuck them in now before topping with the remaining bread slices to complete your sandwiches
Butter the exterior:
Spread softened butter generously on the outside of each sandwich, covering both top and bottom completely for that even golden crunch
Grill to perfection:
Heat your skillet over medium heat, place the sandwiches inside, and press gently with your spatula for about three to four minutes per side until deeply golden and the cheese has melted completely
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Soft, absorbent towels keep counters dry while cooking, wiping spills, and handling dishes during everyday recipe prep.
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Mozzarella Pesto Chicken Grilled Cheese sandwich cut in half, revealing gooey cheese and savory chicken layers.  Pin it
Mozzarella Pesto Chicken Grilled Cheese sandwich cut in half, revealing gooey cheese and savory chicken layers. | cozybatbout.com

My oldest daughter now requests these for sleepovers, and her friends always ask for the recipe. The best part is watching them try to figure out what makes these so different from regular grilled cheese, until someone spots the green peeking through the cheese.

Bread Selection Secrets

Sourdough gives you that tangy backbone and structural integrity, while Italian bread offers a softer, more pillowy interior. Ciabatta creates incredible air pockets that get wonderfully crisp, but multigrain can add a nutty dimension that plays beautifully with the pesto. Whatever you choose, avoid sandwich bread that's too soft or it'll turn mushy instead of achieving that perfect golden crust.

Make Ahead Magic

You can absolutely assemble these sandwiches up to four hours ahead, wrap them tightly in parchment, and keep them refrigerated. The flavors actually meld during this rest time, creating an even more cohesive taste experience. Just don't butter the exterior until right before cooking, or the bread will absorb the butter and lose that signature crunch.

Perfect Pairings

A crisp glass of Pinot Grigio cuts through the richness while echoing the herbal notes in the pesto. For something non-alcoholic, try sparkling water with a wedge of lemon—the acidity brightens every single bite. A simple arugula salad dressed with lemon vinaigrette makes this feel like a complete meal without overwhelming the palate.

  • Keep a small bowl of warm marinara on the side for dipping
  • A handful of salt and vinegar chips adds the perfect salty crunch contrast
  • Slice sandwiches diagonally for easier eating and prettier presentation
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Homemade Mozzarella Pesto Chicken Grilled Cheese on a wooden board, served with a side of marinara. Pin it
Homemade Mozzarella Pesto Chicken Grilled Cheese on a wooden board, served with a side of marinara. | cozybatbout.com

Hope this becomes one of those recipes you make without even thinking, the kind that feels like home no matter what kind of day you've had.

Recipe FAQs

Can I use different types of bread?

Absolutely. While sourdough and Italian bread work beautifully, try ciabatta, focaccia, or multigrain bread for different textures and flavors. Choose sturdy bread varieties that hold up well to butter and pressing.

How do I ensure the cheese melts properly?

Use medium heat and cook for 3-4 minutes per side. Press the sandwich gently with a spatula to ensure even contact with the pan. Fresh mozzarella melts quickly, so watch carefully to prevent the bread from browning too fast.

What's the best chicken to use?

Rotisserie chicken works wonderfully for convenience and flavor. If cooking fresh, use chicken breast and shred it while warm. Shredded turkey breast is also an excellent alternative.

Can I make this vegetarian?

Yes. Swap the chicken for grilled vegetables like zucchini, roasted peppers, or eggplant. You can also add sun-dried tomatoes or caramelized onions for extra depth and richness.

What are good side pairings?

Serve with a crisp Italian white wine, sparkling water with lemon, or fresh tomato soup. Arugula salad with lemon vinaigrette complements the rich, savory flavors beautifully.

How do I store leftovers?

These are best enjoyed fresh. If you have leftovers, store them in an airtight container in the refrigerator for up to 2 days. Reheat in a skillet over medium heat until warmed through and cheese melts again.

Mozzarella Pesto Chicken Grilled Cheese

Juicy shredded chicken, vibrant pesto, and gooey mozzarella pressed into golden, savory perfection.

Prep duration
10 minutes
Cook duration
10 minutes
Overall time
20 minutes
Recipe by Noah Kendrick


Skill Level Easy

Cuisine American/Italian Fusion

Makes 2 Portions

Diet Info None specified

What You Need

Bread & Dairy

01 4 slices sourdough or Italian bread
02 4 oz fresh mozzarella, sliced or shredded
03 2 tablespoons unsalted butter, softened

Protein

01 1 cup cooked, shredded chicken breast

Sauces & Spreads

01 3 tablespoons basil pesto

Optional Add-Ins

01 2 tablespoons grated Parmesan cheese
02 1 small tomato, thinly sliced
03 Fresh basil leaves

Directions

Step 01

Prepare Bread: Lay out four bread slices. Spread 1 to 1.5 tablespoons pesto onto two slices.

Step 02

Layer Chicken: Evenly distribute 1 cup shredded chicken breast on top of the pesto-covered slices.

Step 03

Assemble Toppings: Layer mozzarella cheese over chicken. Add tomato slices and fresh basil if using. Sprinkle with Parmesan cheese for extra flavor if desired.

Step 04

Form Sandwiches: Top with remaining bread slices to create sandwiches.

Step 05

Butter Exterior: Spread softened butter on the outside of each sandwich on both top and bottom surfaces.

Step 06

Cook Sandwiches: Heat a large skillet or grill pan over medium heat. Place sandwiches in pan, pressing slightly with spatula. Cook for 3 to 4 minutes per side until bread is golden brown and cheese is fully melted.

Step 07

Finish & Serve: Remove from skillet and let rest for 1 minute. Cut each sandwich in half and serve warm.

Tools Needed

  • Skillet or grill pan
  • Spatula
  • Knife
  • Cutting board

Allergy Notice

Check every item for allergens and ask a health expert if unsure.
  • Contains dairy: mozzarella, butter, Parmesan
  • Contains wheat and gluten from bread
  • May contain tree nuts if pesto contains pine nuts
  • Store-bought pesto may contain additional nut and cheese allergens

Nutrition details (per portion)

Nutrition details are for general reference. Don’t substitute for professional advice.
  • Calorie count: 520
  • Fat content: 27 g
  • Carbohydrates: 32 g
  • Proteins: 36 g